Etoposide  (Eposin®, Etopophos®, Vepesid®, VP-16®)

 

This is part of the ESHAP treatment, and is given on days 1 – 4 inclusive.

 

Possible side effects

 

Bone Marrow

A temporary reduction in bone marrow function, which can also result in bruising or bleeding and infection.

This effect can begin about 7 days after the treatment has been given and usually reaches it lowest point at 10-14 days after the chemotherapy, increasing steadily thereafter.

 

Hair Loss

This usually starts 3 – 4 weeks after the first dose, although it may occur earlier, and can include eyelashes, eyebrows and other body hair. This is temporary and your hair will return once treatment is finished.

 

Nausea and Vomiting

Can be controlled with medicine.

 

Less Common Side Effects

 

Diarrhoea

Can easily be controlled with medicine.

 

Loss of Appetite

If this becomes a problem, discuss it with your consultant, who can refer you to a dietician.

 

Temporary Taste alterations

If this becomes a problem, discuss it with your consultant, who can refer you to a dietician.

 

Mouth sores and ulcers

Mouth washes and creams are available to help if you develop mouth problems.

 

Skin changes

You may develop a rash which may be itchy.

 

Sleeplessness, headache and confusion

Very rare, but let the doctor know immediately if any of these side effects occur.

 

Allergic Reaction

Can include skin rashes, itching, high temperature, shivering, redness of the face, dizziness, headache, shortness or breath, anxiety and a need to pass urine.

Tell your doctor if any of these develop.

 

Fertility

Your ability to conceive or father a child may be affected by taking this drug.

 

Contraception

It is not advisable to become pregnant or father a child while taking this drug.

 

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